Imbalances in brain chemicals — including serotonin, which helps regulate pain in your nervous system — also may be involved. Find relief from orgasm headache Triptans and SSRIs or SNRIs may be used together, but it's important to watch out for possible symptoms of serotonin syndrome such as changes in cognition, behavior and muscle control such as involuntary jerking. These medications naturally raise serotonin levels, and it is possible that combining them could cause levels that are too high. The pain usually doesn't last very long, though in some cases it may last for several hours. Sometimes, it is others of us with it. Migraines may be caused by changes in the brainstem and its interactions with the trigeminal nerve, a major pain pathway.
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